Levothyroxine (Levothyroxine Sodium,T4)

Levothyroxine sodium is an excellent fat burner since your metabolism is greatly increased while being on it. You can afford to be a little sloppier on precontest dieting since it will still burn fat when you are taking in a lot of calories since your metabolism is going haywire.

Bodybuilders love this product for many reasons. This product is an excellent fat burner since your metabolism is greatly increased while being on it. You can afford to be a little sloppier on precontest dieting since it will still burn fat when you are taking in a lot of calories since your metabolism is going haywire. Step over Ripped Fuel, E/C/A stack, Thermodrine.

When taken with clenbuterol, this is the single best fatburning combination that is available today (with the possible exception of DNP). It also helps to make steroids more effective since it is such a good aid for protein synthesis. Most people need to be careful to start with a low dosage, about 25 mcgs. per day and increase by about one tab or 25 mcgs per day every 5-6 days. Make sure that you don't go over 100 mcgs. per day at the very most. On days that you take muliple tabs, divide the tabs evenly across the day (i.e. 100 mcgs. would be 4 doses of 25 mcgs. apiece spread evenly across the day.) You also need to make sure that you cycle down off this product as well to keep the thyroid functioning properly as well. Don't take for more than 5 weeks at a time as well. After doing a cycle of this drug, make sure you go at least 8 weeks before doing it again as to allow normal thyroid functioning to return.

Levothyroxine, also known as L-thyroxine, synthetic T4 or 3,5,3',5'-tetraiodo-L-thyronine, is a synthetic form of thyroxine (thyroid hormone). The natural hormone is chemically in the L-form, as is the pharmaceutical agent. Dextrothyroxine (D-thyroxine) briefly saw research as an anticholesterol agent but was pulled due to cardiac side-effects.

Common brand names include "Thyrax", "Euthyrox", "Levaxin", "L-thyroxine" and "Eltroxin" in Europe, and "Levoxyl" and "Synthroid" in the United States. There are also numerous generic versions approved by the Food and Drug Administration.

Uses

This medicine is a hormone replacement usually given to patients with thyroid problems, specifically, hypothyroidism. It is also given to people who have goitre or an enlarged thyroid gland.

Administration

It is recommended that levothyroxine be taken with an empty stomach approximately half an hour to an hour before meals to maximize its absorption. It is also recommended that the patient take the tablet with one glass of water to ease swallowing as well as to help the tablet dissolve for absorption.

Dosage, precautions and side effects

Dosages vary according the age groups and the individual condition of the patient, body weight and compliance to the medication and diet. Maximum dosage may reach 400 mcg per day but that is rare. Monitoring of the patients condition and adjustment of the dosage is periodical and necessary.

There are also foods and other substances that can interfere with absorption of thyroxine replacement. Avoid taking calcium and iron supplements within 4 hours of the medication and avoid taking soy products within 3 hours of the medication as these can reduce absorption of the medication. Other substances that reduce absorption are aluminium and magnesium containing antacids, simethicone or sucralfate, Cholestyramine, colestipol, Kayexalate. Other substances cause other adverse effects that may be severe. Ketamine may cause hypertension and tachycardia and Tricyclic and tetracyclic antidepressants increase its toxicity.On the other hand Lithium causes hyperthyroidism by affecting iodine metabolism of the thyroid itself and thus inhibits Synthetic levothyroxine as well.

Synthetic levothyroxine may have adverse side effects like: palpitations, nervousness, headache, difficulty sleeping, insomnia, swelling of the legs and ankles, weight loss and/or increased appetite. Allergies to the medicine are unlikely, but if the patient develops a severe reaction to this drug such as difficulty breathing, shortness of breath or swelling of the face and tongue it is imperative that the patient immediately seek medical attention.

Acute overdose may cause fever, hypoglycemia, heart failure, coma and unrecognized adrenal insufficiency. Acute massive overdose may be life-threatening; treatment should be symptomatic and supportive. Massive overdose may be a require beta-blockers for increased sympathomimetic activity.

The side effects of overdosing appear 6 hours to 11 days after ingestion.

FDA approved, in most states no prescription required.