Xenical

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Xenical (Orlistat)

Using Directions

The drug is prescribed for the frankly obese and for merely overweight people who have other health problems such as high blood pressure, diabetes, or high cholesterol levels. Your weight status is determined by your body mass index (BMI), a comparison of height to weight.

Along with dietary fat, Xenical decreases the absorption of some fat-soluble vitamins and beta-carotene. To compensate, you should take a multivitamin containing vitamins A, E, D, and K once a day, at least 2 hours before or 2 hours after taking Xenical

Do not take Xenical if you suffer from "chronic malabsorption syndrome"—a condition that prevents nutrients from passing from your stomach into your bloodstream—or from cholestasis, a blockage in the supply of bile needed for digestion. You’ll also need to avoid Xenical if it gives you an allergic reaction.

Take a capsule of Xenical during, or up to 1 hour after, each main meal. You should follow a nutritionally balanced, low-calorie diet that provides no more than 30 percent of its calories from fat. If you miss a meal, or the meal contains no fat, you can skip the accompanying dose of Xenical.

If you miss a dose, resume taking Xenical at the next meal. Don”t try to make up the loss with a double dose. The extra drug won”t help.

Store at room temperature, in a tightly sealed container.

Cautions

Weight loss begins within 2 weeks and continues for 6 to 12 months. The effect of using Xenical for more than 2 years is still unknown.

Side effects such as diarrhea and abdominal pain may be worse if you continue eating a high fat diet or even take a high-fat meal. Limit your fat intake.

Your doctor will test your thyroid function before starting you on Xenical to make sure that your weight problem is not due to an underactive thyroid gland (hypothyroidism). Xenical is not an appropriate remedy for this problem.

Xenical increases the likelihood of kidney stones. Use it with caution if you have a history of this problem.

If you have diabetes, weight-loss is likely to reduce your blood sugar levels. If you”re taking an oral diabetes medication or insulin, your dose may have to be reduced.

Note that the safety and efficacy of this drug in children have not been established.

Possible Side Effects

Side effects of Xenical are more common during the first year of treatment. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Xenical.

More common side effects may include: Abdominal discomfort or pain, anxiety, arthritis, back pain, diarrhea, dizziness, earache, fatigue, fatty or oily stools, fecal urgency or incontinence, flu, gas with fecal discharge, gum problems, headache, increased defecation, menstrual problems, muscle pain, nausea, oily discharge, rectal discomfort or pain, respiratory tract infections, skin rash, sleep problems, tooth problems, urinary tract infections, vaginal inflammation, vomiting

Less common side effects may include: Dry skin, ear/nose/throat problems, joint disorders

Side effects that usually occur after the first year of treatment with Xenical include: depression, leg pain, swollen feet, and tendonitis.

Possible food and drug interactions

If Xenical is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Xenical with the following:

Cyclosporine (Neoral and Sandimmune)

Pravastatin (Pravachol)

Warfarin (Coumadin)

The effects of Xenical during pregnancy have not been adequately studied and the drug is not recommended for pregnant women. If you are pregnant or plan to become pregnant, inform your doctor immediately.

It is not known whether Xenical appears in breast milk. Do not take it while breastfeeding

Dosage instructions

For adults recommended dose is one 120-milligram capsule 3 times daily with each main meal containing fat.

The results of a massive overdose of Xenical are unknown, although the drug seems relatively harmless. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention.

XenicalTM is a registered trademark of F. Hoffmann-La Roche Ltd

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Ventolase (Clenbuterol, Albuterol/Ventolin, Salbutamol)

Details:
hemical Name: Albuterol Sulfate
Drug Class: Beta-Agonist

Albuterol (Salbutamol) as a much better alternative to clenbuterol due to lesser side effects. Albuterol is a (relatively) selective beta-2 adrenoreceptor agonist, just like Clenbuterol. Clen is simply too harsh on most people; they get too jittery, too shaky, and too anxious. It’s a lot to go through to burn some fat.

Albuterol produces a much “cleaner” type of stimulant effect than Clenbuterol. I don’t know how to really describe this other than to say that the “Clen-shakes” just aren’t as bad with Albuterol in addition, I’m able to focus better on my work when I use Albuterol, while with Clenbuterol I’m stimulated but not really focused. But even though Albuterol produces a much cleaner stimulant-type feeling in most people, the main question is “How well does it burn fat”? As far as fat-burning stimulants go, how does it stack up to Clenbuterol? Lets face it, most people are really only concerned with the end results, right? Well, at least in me and the people I’ve worked with, Albuterol seems to produce significantly better results than Clen in terms of fat burning effects and it produces them just a bit more quickly too. This makes sense, if you think about it.

Albuterol is often thought of as a “shorter acting” version of Clen and, to draw an analogy, when we look at the steroids which are shorter acting versions (think about comparing something like Testosterone Propionate vs Cypionate, or NPP vs Deca-Durabolin) – they typically produce more dramatic results a bit quicker than their long acting cousins. I’m finding the same thing to be true with Albuterol. When we take a look at a medical study examining Clenbuterol vs. a beta-2 agonist which has an even longer half life (“Salmeterol”), we see that Clen out performs it in terms of anabolic effects. So I think it would only be logical to assume that something that was a shorter acting beta-2 agonist than Clen would likely outperform it, right? Let me just restate that, to make sure we’re all on the same page, ok? Clenbuterol outperforms longer acting beta-2 agonists, in terms of anabolic effects. Albuterol is a beta-2 agonist with a shorter acting effect than Clenbuterol. Therefore, it’s only logical that Albuterol is going to be more anabolic than Clen, right? Ok, let’s move on

To understand how Albuterol works, first we need to take a look at the Beta adrenergic system. This system is comprised of something called adrenoreceptors, and the most well known (to bodybuilders anyway) of the adrenoreceptors are the beta receptors. Beta receptors are embedded in the cell’s outer phospholipid membrane, and are stimulated by all the really popular stimulants ephedrine, Clenbuterol, etc… These receptors can further be divided into three subtypes: 1, 2, & 3, (of which we are primarily concerned with type-2, because the type-3 variety seems to primarily be less relevant in humans than in other animals, and because Albuterol doesn’t stimulate the type-1 receptor). There also exists a type of receptor known as an alpha receptor, which isn’t relevant here, but warrants a brief explanation. Alpha receptors differ from beta receptors in that they are activated at significantly lower catecholamine levels than are the beta receptors. A catecholamine is simply an organic compound that affects the sympathetic nervous system. For example, dopamine, norepinephrine and epinephrine are all catecholamines.

We are, mostly concerned with Beta-2 receptors, because those are what we see stimulated with Albuterol. It should come as no surprise to anyone who has used Clenbuterol as well as Albuterol is that when you stimulate your beta receptors, it causes something called vasodilatation (increased blood flow). Stimulation of these receptors also stimulates the break down of fatty acids into the blood stream for use as fuel, which causes a reduction in stored fat. Of course, this increased blood flow also comes with an increased heart rate. This explains how Beta-2 adrenergic stimulation can also increase your body temperature a bit however this isn’t something that’s too noticeable on a thermometer most people will feel a bit hotter, and some will even break a sweat (I fall into the latter category). Beta-agonists work to do this by increasing heat production in the cell’s owerhouse, the mitochondria, which will also increase your basal metabolic rate, and decrease your appetite. Not too many people feel hungry after a whopping dose of stimulants.

There is also some evidence that Beta-Agonists are anabolic (more properly, however, this would actually be anti-catabolic). This is because Beta-agonists also act to initiate a hormonal cascade that involves the activation of a compound called cAMP (basically: cyclic-Adenosine Monophosphate). After this, cAMP activates calpistatin that is the inhibitor of calpain. Calpain works to degrade protein in skeletal muscle (among other functions). Therefore, we already saw that how stimulation of beta 2 receptors have the ability to increase energy expenditure and free up body fat to be used as fuel, and now we have some understanding of how that stimulation can also have the potential to be anti-catabolic as well . Now that we’re all on the same page regarding the beta-adregenic system, and what sorts of effects we can expect when we stimulate it with beta-2 agonists lets take a more specific look at Albuterol, and why I think it’s such a great compound.

When we take a look at Albuterol’s ability to burn fat, it’s clear that it has the ability to aid fat loss in both normal as well as obese men . That’s not very different from Clenbuterol, in any way. However, in my personal experience with it, I think that Albuterol really outperforms Clen in areas of strength gains as well as for athletic purposes .lets take a look at my claim and see how Albuterol performs in humans In one study, subjects were given Albuterol and performed 9 weeks of isokinetic knee extensions (there was also a group who performed the same exercise routine but were not given Albuterol). The Albuterol group, predictably, had better strength gains than the non-Albuterol group (only a therapeutic dose was given). In my own experience, strength gains with Albuterol are much better and seen more quickly than I see them with Clen. In fact, while I don’t particularly experience much of a performance enhancing effect from Clen in the gym; on the other hand I see strength gains and muscular improvements within the first couple weeks of using Albuterol. Of course, this is likely a pure anabolic effect and probably not easily explained as a simple “enhanced” anti-catabolic effect, and likely can’t be explained away with the Calpain idea you read about earlier.

I still think that I can take a pretty good shot at explaining why Albuterol is anabolic, though. strong body of evidence exists to suggest that Albuterol influences the release of cAMP. As you may know, cAMP also plays an important role in mediating certain catecholamines secreted by the adrenal medulla have an inhibitory effect on muscle dependent protein degradation, but in addition, norepinephrine released from adrenergic terminals may actually increase the rate of protein synthesis(not just decrease the rate of their degradation) in oxidative muscles, thereby leading to increased protein accretion (representing a true anabolic effect). That’s most likely the way that we receive part of the anabolic effect from Beta-stimulation. Another way is perhaps through the beta-adrenergic stimulated lowering of “Interleukin-6” from fat cells (long story ). Anecdotally, Clenbuterol and ephedrine have both shown themselves capable of temporarily increasing strength, and I would bet most beta-agonists have this effect, but I don’t think has been shown as conclusively in the medical literature as it has been with Albuterol.

Albuterol has been shown to increase muscle size (3-6) as well as strength and endurance (*while people have anecdotally reported that Clen seems to lower their aerobic capacity. Clenbuterol has a disadvantage when compared with Albuterol in the area of strength gains, probably due to the act that it use-dependently inhibits action potential firing in skeletal muscle fibers, which is not directly caused by inherent Beta-2 stimulant activities . I think that’s the best quasi-scientific explanation I Again, my own personal experience and that of my research assistant(s) would also seem to strongly support this claim all of us have gotten leaner, bigger and stronger with the use of Albuterol, while with Clen, we got more ripped but not really stronger (and certainly not much bigger). Anecdotally, we’ve seen Clenbuterol fall a bit flat when people use it for anabolic effects, although in animals it would appear to be highly anabolic, though human studies are a bit shaky (ha!) in this area.

One of the things I really like about Albuterol is that it has the potential to actually be used on my cycle to make it safer by improving my lipid profile (cholesterol) or during PCT to help get my cholesterol levels back in check. This is because Albuterol shows significant benefits to cholesterol as it works to lower total cholesterol, specifically LDL (the bad stuff) while at the same time elevating HDL (the good stuff).

In my own particular case, cholesterol never seems to be an issue, but now that I’m working with Oasis for HRT, it’s certainly in my best interests to show up every three months with nice looking blood work.

So now is the part you’ve been waiting for (*or the part you skipped to, ignoring the rest of the article whatever ). How much of this should you take, and how often? Well, I can tell you that I have found the best results by working my way up from 4mgs taken once a day, up to 4-8 mgs taken 3x a day. I know that some people will think that 24ms a day of this stuff is going to be too much (it is, after all, a stimulant). But I can tell you that I have a pretty good tolerance for stimulants (I’ve taken up to 200 mcg/day of Clenbuterol, and some other pretty hefty stimulants that I probably shouldn’t mention in polite company). Most people are going to find their sweet spot at about 4mgs of Albuterol 3x a day or so women will probably take about half that dose, and be fine with it. I think that Albuterol is about to become very popular, very soon and I, for one, am looking forward to seeing less of my old Clen article around the ‘net, and more of this one.

For oral dosage form (syrup, tablets):
Adults and children older than 12 years of age—2 or 4 milligrams (mg) taken 3 or 4 times per day.
Your doctor may increase your dose as needed up to a maximum of 32 mg per day, divided and given 4 times per day

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Clenbuterol [Clen buterol HCL tabs]

General

Clenbuterol is a β2 adrenergic agonist with some similarities to Ephedrine, but its effects are more potent and longer-lasting as a stimulant and thermogenic drug. It causes an increase in aerobic capacity, CNS stimulation, and an increase in blood pressure and oxygen transportation. It increases the rate at which fat and protein is used up in the body at the same time as slowing down the storage of glycogen. It is commonly used for smooth muscle relaxant properties. This means that it is a bronchodilator and tocolytic. It is usually used in dosages anywhere from 20-60 micrograms a day when prescribed. A dose of about 150 μg should never be exceeded in a day. It is also prescribed for treatment of horses, however, equestrian usage is usually the liquid form of Clenbuterol. It works under the PNS-sympathetic.

The substance Clenbuterol-hydrochloride is also available in various other forms of administration, including syrups, drops, liquids, dosing aerosols, injectable solutions, and granules. Since athletes usually prefer tablets, manufacturers and trade names offering this oral version are listed.

Clenbuterol is a very interesting and remarkable compound. It is not a steroid hormone but a beta-2-symphatomimetic. Its effects, however can by all means be compared to those of steroids. Similar to a combination of Winstrol Depot and Anavar, Clenbuterol can cause a solid, highly qualitative muscle growth which goes hand in hand with a significant strength gain. Clenbuterol, above all, has a strong anticatabolic effect, which means it decreases the rate at which protein is reduced in the muscle cell, consequently causing an enlargement of muscle cells. For this reason, numerous athletes use Clenbuterol after steroid treatment to balance the resulting catabolic phase and thus obtain maximum strength and muscle mass.

A further aspect of Clen is its distinet fat-burning effect. It burns fat without dieting because it inereases the body temperature slightly, forcing the body to burn fat for this process. Clenbuterol, in the meantime, is not only a favorite competition compound among professional bodybuilders. An especially intense fat-burning occurs when Clen is combined with the LT3-thyroid hormone compound Cytomel. Due to the higher body temperature Clenbuterol magnifies the effect of anabolic/androgenic steroids taken simultaneously, since the protein processing is increased. The dosage depends on body weight and can be optimized by measuring the body temperature. Athletes usually take 5-7 tablets, 100-140 mcg per day. For women 80-100 mcg/day are usually sufficient. It is important that the athlete begin by taking only one tablet on the first day and then increasing the dosage by one tablet each of the following days until the desired maximum dosage is reached. Following, there are several schedules for taking Clenbuterol.

On the one hand, emphasis is placed on the burning of fat; on the other hand, importance is placed on a balanced relationship between strength and muscle growth as well as fat reduction. The compound is usually taken over a period of 8-10 weeks. Since it is not a hormone compound it has no side effects typical of anabolic steroids For this reason it is also liked by women. Possible side effects of Clenbuterol include restlessness, palpitations, tremor (involuntary trembling of fingers), headache, increased perspiration, insomnia, possible muscle spasms, increased blood pressure, and nausea. Note that these side effects are of a temporary nature and usually subside after 8-10 days, despite continuation of the product. Throughout Europe the substance Clenbuterol hydrocloride must be prescribed by a physician. Clenbuterol is not officially available in the U.S.

 

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