Jintropin (HgH – Human Growth Hormone)
HGH is being produced by pituitary gland in the human body. This peptide plays vital role in human body and is responsible for many different things, including muscle and bone development. As one gets older, the level of endogenous HGH in the body decreases. Normal growth is impossible without this hormone and it acts throughout the whole life. Jintropin HGH injections are still beneficial for adults, especially to competing sportsmen. For elderly people HGH replacement therapy is a part of anti-aging therapy. Injections raise HGH levels back to the youth-like ones thus improving muscle growth, weight loss and defeating aging.
Jintropin is one of the purest and the most famous recombinant human growth hormone (rHGH) brands, it’s quality is par to very expensive American-made Humatrope although notably cheaper. Jintropin kit contains 10 vials, each one 10IU or 4 IU (this is new version) thus making 100IU or 40IU per kit, respectively.
Jintropin comes as a white lyophilized powder (it should not look as a distinct disk) consisting of the 191 amino acids sequence identical to endogenous human growth hormone. Various HGH brands differ in quality (purity) of substance, the more pure it is the less is possibility of developing antibody resistance, which may in theory decrease effectiveness of the drug. Some of the cheapest rHGH brands consist of 192 amino acids formula, which differs from natural. It works more or less for vast majority of people but for some could be completely ineffective. There’s also liquid version called Jintropin AQ.
Jintropin export from China officially ceased since Spring 2008 due to US pressure on Chinese government in connection with Olympic Games. Most of Jintropin on the Western over-the-counter market is fake! Only big pharmaceutical companies with official import license are able to purchase from GenSci now. Therefore, you can find this product only with prescription in legal retail pharmacies, not from various overseas online stores. However, we do not say that absolutely all Jintropin on the black market is fake. There is still limited number of channels available through domestic Chinese resellers at huge price.
The website of the manufacturer is GeneScience Pharmaceutical Co., Ltd. and their code-checking center http://www.gensci-china.com/gensci/center-anti.html. A clone website http://www.jintropin.cn is FAKE and has no relation to Gensci, as well as plenty of other fake sites.
Peptides play vital role in human’s body and are related among themselves in various ways. HGH is a part of following chain GHRH (or artificial CJC-1295 with DAC hormone) -> HGH->IGF1->MGF. Growth Hormone Releasing Hormone initiate producing of HGH. HGH itself has several positive effects and also works by increasing the volume of another peptide called IGF-1 (insulin-like growth factor) . IGF-1,in turn, increases the number of muscle cells and produces MGF (mechano growth factor), which works towards repairing damaged cells. As a result muscle density is notably increased, body fat decreased and ageing process is being slowed down.
Combinations like CJC-1295 plus GHRH-6 or HGH along with IGF-1 Long R3 or HGH+IGF-1 LR3+MGF at sufficient dosages produces unbelievable synergetic effect, which could not be reached simply by increasing HGH dosage. Most likely the reason is maintaining higher and more stable hormone levels in the blood for a long time, which is impossible to maintain with HGH only due to quite short halflife. However, in most occasions even using HGH standalone at proper time of a day is sufficient to reach athlete’s goals, one just must consider level peaks and downs.
After puberty, it became more difficult to increase number of muscle fibers, training mostly increases number of muscle cells for existing fibers or their volume due to water retention. HGH assists in raising levels of IGF-1 back to their pre-pubescent level, hence helping muscle fibers to split and creating new ones thus making more relief and more determination of all muscles.
HGH allows athletes to develop and maintain the ideal muscle density. Unlike steroids which may cause you to gain so-called water weight, it promotes only lean muscle growth. Thus HGH indirectly but very effectively increases lean body mass, shortens recovery time in-between workouts, and enhances the overall performance with less risk of detection than steroids. In addition, it strengthens joints and ligaments and cures damaged tissue. Also HGH promotes protein synthesis abilities, increases volume of insulin a body can effectively use. It well complements steroids improving their effectiveness, so in most cycles HGH comes together with anabolics.
HGH raises person’s energy levels and increases metabolism, so adults can benefit the same energy as they did when they were young. An increased metabolism also means an increased burning of fat. In fact, HGH (Jintropin and other brands) can cause weight loss even without exercise.
Human growth hormone is one of the most effective drugs in this area. With age production of all hormones including HGH falls down, body becomes less and less able to repair damaged cells and produce new ones. HGH improves cells restoration as well as new cells production thus making it useful virtually in any system of the body. Jintropin HGH promotes smoother and less-wrinkled skin by repairing damaged skin cells. Also it helps in strengthen bones , even those that have been damaged by osteoporosis. In addition, it can repair damaged brain cells and hence prevent memory loss. It’s anabolic (muscle-improving) effects have been already discussed.
Human growth hormone is not new thing in medicine. Some major pharmaceutical companies have been manufacturing HGH for many, many years. However, it was extremely expensive and only prescribed to the children with low or non-existent endogenous HGH. Bodybuilders have to acquire it on the black market; Jintropin is very potent brand of HGH, it is similar to American brand Humatrope, but much less expensive.
HGH in the sport (bodybuilding)
HGH provides plenty of benefits to the athletes. It’s safer than using steroids and it well complements steroid cycles. Human Growth Hormone stimulates growth of many body tissues, mostly due to increase in cell number rather than size. This includes skeletal muscle tissue, and with the exception of eyes and brain all other body organs. It improves the transport of amino acids, as well as the rate of protein synthesis.
Actually, most of these positive effects are caused by IGF-1 (insulin-like growth factor). This is a highly anabolic hormone produced in the liver and other tissues in response to GH. Maximum levels of IGF-1 are observed approx. 20 hrs after HGH administration. HGH itself stimulates triglyceride hydrolysis in adipose tissue, which leads to notable melting of fat. Also it increases glucose output in the liver, and induces insulin resistance by blocking the activity of this hormone in target cells. A shift is seen where fats become primary source of energy, further enhancing fat loss.
Strength of connective tissues, cartilage and tendons is also enhanced thus reducing possibility of injures during training with heavy weights.
Usage of HGH
This is very dosage-dependent drug. Using low dosages or low frequency of injections is a waste of money! Also, it should be applied long enough to become effective – 8-12 weeks at least, better more. If you fail to meet these requirements, the results will be very poor. If you cannot afford full-scale HGH cycle, you should really avoid using it.
The average male athlete daily dosage ranges between 5 to 10 I.U. to achieve the best results. On the low end perhaps 2 to 6 I.U. can be used ED (or 8 I.U. EOD, administered during ‘training’ days).
Daily dosing is important, as HGH has a very short life span in the body. Peak blood concentrations are noted quickly (2 to 6 hours) after injection, and the hormone isquickly cleared from the body with a half-life of only 20-30 minutes. Some athletes advise using it EOD (duplicate dosage) as it is more effective like this. The trick is to use it during workouts, not days-off. If you are using let’s say 5 IU ED then EOD dosage comes to 10 IU.
The effects of this drug are also most pronounced when it is used many months long. Shorter HGH cycles (4 weeks) are effective for fat-burn but not muscle-growth.
This drug can be injected both – intramuscular and subcutaneous. “Sub-Q” injections produce localized melting of fat, thus requiring to change injection spots to even out the effect. General fat-burn also takes place, it appears more quickly and is less dependent on dosage.
Although it’s not absolutely necessary, using of supplemental drugs could produce even better effects. HGH injections suppress endogenous thyroid and insulin production, while your body requires increased amount of thyroid hormones, insulin and androgens during treatment.
Adding thyroid hormones like T3 (cytomel, tiromel brands) and T4 (synthroid) also known as liothyronine and levothyroxin substances, will greatly increase the thermogenic effectiveness of a cycle. The more powerful T3 is usually preferred at daily dosage of 25 mcg.
Insulin could be also very useful. Aside from replacing lowered insulin levels, use of this hormone is important as it can increase receptor sensitivity to IGF-1, and reduce levels of IGF binding protein-1 thus allowing more free IGF in the blood.
Adding HGH derivatives – IGF (Insulin-like Growth Factor) and MGF (Mechano Growth Factor) to the cycle produces synergetic effect.
Steroids also proved to be very effective to benefit full anabolic effect of HGH. It’s better to use something with a strong androgenic component, for instance testosterone or trenbolone (parabolan) if estrogen levels matter. While HGH increases cell count, androgens increases cell volume. Using of AAS may also increase free IGF-1 levels.
The combination of all mentioned drugs – HGH (maybe along with IGF/MGF), anabolic steroids, insulin and T3 proved to be the most effective combination with great synergetic effect and clearly amplified results. However, one should always consider potential risks related to the usage of thyroid hormones and insulin, which could cause serious health problems unless used wisely.
Resume: HGH could very effective drug if athlete well understands what he is using it for. Standalone it will not turn you into “freaky monster”, if all you need is mass – better go to classic bulking steroids. If you need to cut down – better use special fat-burning drugs. Also, if comparing $ to $ investments, anabolic steroids could do the job cheaper. Using peptides and especially HGH is like a different side of coin with its own pros and cons – more expensive and less sides.
The most prominent results are achieved when combining both types of products – one can benefit from great shape, excellent physique and marvelous performance. But for an amateur sportsmen using of HGH is often like overkill, it mostly necessary for competing athletes where substantial investments are well justified.
More quality HGH brands like Jintropin act much quicker than let’s say Serostim with regards to the results.
Anti ageing: feeling of well being, some moderate fat-burn, improved skin appearance – 2 IU daily
General treatment: moderate fat-burn, improved sleep, more energy: 3 IU daily
Fitness: improved muscles, advanced fat-burn – 4 IU/ED
Sport: muscular hypertrophy, great feeling of a wellbeing, superman energy – 5 IU and more daily. Duplicate dosage could be administered EOD during workouts.
Daily dosage for more effect should be better split on two shots – 8 a.m. (or after wake up) and approx 1 p.m. (or after workout, but not too late). Do not admiister before sleep – it’s a waste. Such schedule allows to get the most profit from combination of endogenous and exogenous Growth Hormone. If splitting is not possible – inject it all in the morning
Hypothalamus releases GHRH (growth hormone releasing hormone, i.e. precursor of GH) and SST (somatostatin). They both stimulate or inhibit the output of GH by the pituitary. GH has direct effects on many tissues, as well as indirect effects via the production of IGF-1. IGF-1 also causes negative feedback inhibition at the pituitary and hypothalamus. Therefore, heightened release of somatostatin affects not only the release of GH, but insulin and thyroid hormones as well.
Human Growth Hormone by itself carries certain risks. The most feared and the most discussed side effect would be acromegaly, or a noticeable thickening of the bones, especially the feet, forehead, hands, jaw and elbows. The drug can also enlarge vital organs such as heart and kidneys, and has been linked to hypoglycemia and diabetes (presumably due to its ability to induce insulin resistance). In theory, excessive usage of this hormone can lead to a number of conditions, some of them life threatening. Fortunately, such problems are extremely rare and unlikely to occur if used periodically in moderate dosages. Among the many athletes using growth hormone, there are very few documented cases of a serious health problems developed.
Of course, if there are any noticeable changes in bone structure, skin texture or normal health conditions HGH therapy must be ceased immediately.
Detection and doping control.
Not long ago it was absolutely “safe” drug for testing. However, recently some test have been invented. It’s difficult to evaluate yet how accurate they are and how long is detection time (must be very short, like several days). However, HGH is still advisable for competing athletes, risks are much less comparing to using of steroids.
HOW TO STORE HGH
Although this was a big issue in the past, most of modern HGH brands could sustain under room temperature for about a month thus making transportation possible without using dry ice as it was in the past. It is still recommended, however, to decrease “hot” time as much as possible and keep it refrigerated between 2 – 8 degrees Celsius. But never freeze!
For instance, Eurotech brand cannot be kept at room temperature indeed, while Jintropin™ is made according to a special patented technology, so it can withstand temperatures up to 37 degrees Celsius for over a month and 45 degrees Celsius for over a week, which is incredible, unbelievable time. In proper storage conditions it’s good for over a year (until exp. date indicated on the package).
After reconstitution liquid has to be refrigerated. With Jintropin maximum storage time comes to 20 days, with other brands 2-5 days.
SOLUTION WATER REQUIREMENTS (H20)
Water for solution always comes with more expensive Growth Hormone kits, with cheaper brands you have to acquire it separately. When mixing HGH and other peptides into solution, two types of water could be used – either sterile or bacteriostatic one.
Sterile (distilled) water solution meant to be used within a 48 hour period. Bacteriostatic water contains very small volume of acid which allows Growth Hormone to be kept for a longer period of time. The acid makes the bond between the molecules more stable. The sterile water just weakens this bond quickly thus making molecules to become unstable.
For peptides it’s more convenient to use insulin syringes. At-first, they have thin and convenient for this purpose pin. At-second, the syringe itself allows much more precise measuring than “regular” syringes.
1 ml insulin syringe contains 100 marks (100 “clicks”). When you dissolve full HGH bottle in this volume, you can count how much to inject.
Hygetropin 8 IU bottle – every click equals 0.8 IU. In order to make 4 IU injection you have to utilize half of the syringe, i.e. 50 clicks
Jintropin or Kigtropin 10 IU bottle: In this case, every 10 clicks equals 1iu, for 4 IU injection you have to use 40 clicks.
When mixing water with the powder always release it slowly downside the glass. This ensures that the compound remains intact since HGH molecule is long and fragile. Once you filled it with water, gently swirl the solution until dissolved. NEVER SHAKE!
WHERE TO INJECT
It is to be injected virtually anywhere, preferably sub-q. The inner thigh is the area which suits the most for good absorption although many people prefer abdomen area instead due to convenience of the process (however, fat may slow down absorption).
When injecting sub-q set a needle at 45° angle towards the skin surface, carefully pinch a small fold and inject in the middle.
HGH vs IGF vs MGF
Growth Hormone does not directly causes muscle growth, it rather works indirectly by increasing protein synthesis capabilities as well as increasing volume of insulin and anabolics a body can utilize effectively. HGH might be considered as a precursor to IGF while IFG is a precursor to MGF. Each of them could be used standalone although IGF is a bit more effective in direct effect caused to muscle growth and increasing muscle density. It’s difficult to say if any product is “better”. Combining two or all of them together could bring marvellous synergetic effect, just make sure to use versions, which are stable in the blood – Long R3 IGF-1 and pegMGF (pegylated).
GenSci ceased export in 2008 under US pressure in connection with the Olympic Games. Most (although not all) of Jintropin available nowadays on the over-the-counter market is fake. Consider using other top pharm-grade products like Saizen HGH
- HGH increases tissues strength and growth by improved metabolism
- HGH enables faster recovery period
- HGH has strong anti-ageing effect
- You can no longer buy Jintropin (Human Growth Hormone)
- You can buy Saizen (Human Growth Hormone) here