Author: Martin

SARMs

Recently an absolutely new class of performance enhancing drugs was discovered. These drugs were called selective androgen receptor modulators (SARMs). Their initial purpose was increase of muscle mass in cancer patients, and they showed promising results, although not all of them passed through clinical trials.

Since their mass building and fat burning effect was comparable with steroids, they quickly became popular among bodybuilders. What is most important, they had no steroid-specific side effects, such as testicular atrophy, hepatotoxicity, growth of body hair etc.

Why SARMs are better than steroids

Steroids have two types of effect – anabolic and androgenic. Anabolic effect initiate protein synthesis inside muscle cells, which causes muscle growth and has fat burning effect. But
they also affect liver, heart, sex organs and secondary sexual characteristics (e.g. voice deepening, body hair growth, acne etc.). This is androgenic side of steroids.

If we regard testosterone as an example, its anabolic-to-androgenic ratio is 1:1. Meanwhile the anabolic-to-androgenic ratio of SARMs starts from 3:1 and goes up to 90:1. In other words SARMs can provide muscle gains and fat loss without the risks of gynecomastia and virilization.

Unlike most steroids, one can take SARMs orally, which is very convenient. Besides, you can buy SARMs legally. However, in case of changes in the law, SARMs producers and sellers protect themselves from legal issues with the label “for research purposes only” or “not for human use”.

Although there is a lot SARMs, here we will regard the most popular representatives of SARM family. Besides one should mention that most of them are on clinical or preclinical trial. Therefore, if you decided to use them, you do it at your own risk.

MK-2866

Ostarine SARM
Ostarine SARM

MK-2866 (aka Ostarine) induces muscle growth and has fat burning effect. It is probably one of the most studied SARMs. It passed through clinical trials and revealed great results without significant side effects.

During human trials aged men took MK-2866 for 3 months. As a result they gained 3 pounds of muscle mass and lost 1 pound of fat. What is more important, they had no changes in diet or exercises.
The similar results were obtained in cancer patients.

Side effects of MK-2866

These studies revealed no side effects. Nevertheless, there are reports that at high doses for long time (2-3 month) it may temporally suppress testosterone production. However, the levels of testosterone retuned to normal level in two weeks after drug discontinuation.

Doses of MK-2866

There are no official doses for SARMs usage. Therefore, we will regard the most “cautious” doses based on individual reports in forums.

The most optimal dose of Ostarine is 15-20 mg daily for 1 month. Then take a break for 1 month before a new cycle.

You can buy Ostarine (MK-2866) here

LGD-4033

LGD-4033 (VK5211, Ligandrol)
LGD-4033 (VK5211, Ligandrol)

LGD-4033 (aka Ligandrol) went through multiple trials, and revealed very interesting resu lts: It greatly increased lean body mass in healthy men, who took this drug for 3 weeks. The result is dosage dependent, but even 1 mg is enough to accelerate muscle growth significantly.

Even at 22 mg daily it had no side effects or heath issues. In animal trials LGD-4033 showed great increase of bone density, muscle growth, and libido, without any adverse effect on prostate or liver. LGD-4033 has no fat burning effect. Therefore, during solo usage you will get more muscle mass but will not become leaner.

Side effects of LGD-4033

LGD-4033 can temporally suppress endogenous testosterone. However, it rather quickly returns to normal level after discontinuation of the drug (within 3 weeks).

That is to say if the level of your testosterone is low, you should be very careful while taking any SARM.

Doses of LGD-4033

At the dosage 2-5 mg daily for 1 month LGD-4033 will bring you very good results. As the result is dosage dependent, some bodybuilders take up to 15 mg/day. However, it is risky, since it may greatly suppress endogenous testosterone. Take 1 month break between cycles.

You can buy LGD-4033 (VK5211, Ligandrol) here

GW 501516

GW 501516 (Сardarine)
GW 501516 (Сardarine)

GW501516 (aka Cardarine) have no official human trials. In mice it greatly increased endurance. For example during 4 weeks of GW501516 intake mice increased the running time by 68% and running distance by 70 %.

What is more important GW501516 caused growth of mitochondrial in muscle cells. It allows the muscles to produce more power and experience less fatigue. It also has fat burning properties which occur without destruction of muscle fibers. Thus with Cardarine you can improve endurance and get leaner without loss of muscles.

Side effects of GW501516

There are reports that GW501516 can cause cancer. However if we regard the study on which this rumor is based on, we will see that this statement is ridiculous. During this “carcinogenic” experiment mice were taking the human equivalent of 2400 mg a day for 2 years straight. That is 240 times more than the recommended dose, taken every day, for 2 years instead of 1 month!

There is not a single evidence that Cardarine can cause cancer at recommended doses. Besides there are no reports that it can suppress testosterone. Nevertheless, it does not mean that it has no side effects. This is a new drug, and we don’t know everything about it. Therefore, you should take it with caution.

Doses of GW501516

The optimal dosage of GW501516 is 10 mg / day. Divide the daily dosage into two portions. Take 5 mg in the morning and the other 5 in the afternoon. The duration of GW501516 cycle is 4 weeks, and then take 4 week pause before another cycle. You can also combine it with LGD-4033 and MK-2866.

You can buy GW 501516 (Сardarine) here

S4

S4 (aka Andarine) is probably one of the first SARMs which appeared in sports pharmacology. Athletes report moderate strength and muscle gain, and also fat loss. It’s better to combine Andarine with other SARMs, for example MK-2866 and LGD-4033.

Side effects of S4

There are report that S4 can cause visual abnormality, e.g. altered color perception or nighttime blindness. This is probably due to binding of its metabolite to receptor in the eyes. However this side–effect has no official confirmation.

Doses of S4

The optimal dosage is 50 mg daily. Divide it into two (25 mg) portions. Take it for 4 weeks, then make a 4 week gap and then repeat.

SR9009

SR9009 (Stenabolic) increases stamina endurance and produces fat burning effect. Besides it has anti-inflammatory effect and induces growth of new mitochondria in muscle cells.

The only disadvantage of this wonder drug is that it is injectable. Oral intake provides only 2% of bioavailability. However some manufacturers claim that you can take it orally, but it’s not the case

Conclusions

SARMs represent an excellent alternative to anabolic steroids (Testosterone etc.). Some of them are tested for a rather long time and have very good reputation among athletes, for example MK-2866, LGD-4033 и GW501516.

There are several reliable sources where you can buy anabolic steroids:

DecaDurabolin in bodybuilding

Deca-Durabolin (Nandrolone Decanoate) is a powerful steroid for gaining muscle mass. In comparison with testosterone it has very low androgenic activity thou less androgenic side effects. It’s important to know that nandrolone is naturally produced in each person. The half-life of this steroid is 7-10 days.

Like withmany other esterified AAS, it takes time for the organism to detach ester and make this steroid active. That’s why Deca-Durabolin remains active for more than 2 weeks. Its conversion into dihydronadrolone explains low androgenic activity of this steroid, since dihydronadrolone is rather weak substance in comparison to dihydrotestosterone.

Steroid characteristics

  • Duration of activity – 2 weeks
  • Available forms – injection
  • Hepatotoxicity – no
  • Aromatization – low
  • Progestogenic activity – yes
  • Conversion into dihydrotestosterone – no
  • Anabolic properties – 150%
  • Androgenic properties – 30%
  • HPTA suppression – yes
  • Doping tests – detectable during 22 months

The effects of DecaDurabolin

  • Slowly increases muscle mass, but the gains are good.
  • Strengthens the bones
  • Reduces joint pain due to higher production of synovial fluid
  • Improves endurance and immunity

How to use

Medical doses do not provide high anabolic effects. Therefore, the doses for athletes are much higher and vary from 200 mg to 600 mg. The duration of a Deca cycles is about 2 – 2.5 months. It’s important to know that there is certain delay in effect.

Sometimes women take this steroid. Due to progestogenic properties it’s necessary to take Dostinex. Also don’t forget that proper nutrition is important to achieve optimal results. One cannot call Nandrolone Decanoate an ideal steroid, since there are more powerful AAS.
However, unlike those super drugs, Nandrolone is rather safe and suitable for everybody. Therefore it is so popular among athletes.

Combinations

Bodybuilders know that while using Deca the best results can be achieved in combinations with other steroids. Besides, a combination may decrease adverse effects. Usually athletes combine it with Testosterone and Methane.
Here is an example of a very popular mass gaining combination with Testosterone Enanthate.

In order to reduce possible side effects you should include Proviron (Masterlone) and Dostinex into your cycle plan.
A combination of Deca with Methane

PCT is required after each Deca cycle. Remember that :tamoxife: nis not suitable in this case (also after Trenbolone cycles), since it increases the levels of prolactin. Therefore you have to chose between Clomid and Toremifene.

Side effects

Nandrolone has low level of aromatization, which is about 20% in comparison with Testosterone. Thus there are low risks of estrogen related side effects. However, in case of overdose they are possible. You can easily avoid them by taking aromatase inhibitors.

Like all 19-nor steroids, Nandrolone (as well as Trenbolone) has progestogenic activity which can cause estrogen-like side effects, including gynecomastia and water retention. In order to prevent them you should take Dostinex.

As we said above androgenic activity of DecaDurabolin is rather low (about 30% of Testosterone). However, one should remember that threshold of androgenic side effects is higher than in Testosterone or Methandienone.

Thus one cannot negate the possibility of androgenic side effects, which include acne, baldness and hypertrophy of prostate. In women it can cause virilization. We do not recommend to take Finasteride, since it is not effective against dihydronandrolone and may worsen the situation.

Deca is liver friendly, since it is not alkylated. Like all anabolic steroids Nandrolone can change the lipoprotein balance. It leads to reduction of high-density lipoproteins (HDL) and increases the risk of atherosclerosis. This side effect is dosage dependent.

Remember that anabolic steroids negatively affect blood pressure, triglyceride levels, and the ability of blood vessels to relax, which increases the risk of cardiovascular diseases. Thus, you should pay attention to your nutrition plan and include omega 3 fatty acids into your diet.

Nandrolone can significantly suppress HPTA. Scientists suggest that it is due to progestogenic activity of this drug. Therefore in order to avoid this side effect we recommend 0.5 mg of Dostinex two times a week. In case of long cycles it is necessary to take Gonadotropin.

There are several reliable sources where you can buy anabolic steroids:

Androgens

General

Androgens (from Greek “andro” – male) – are male hormones. Testosterone is one of them.
These hormones are responsible for male sexual functions and development of “male” physique. Estrogens are female hormones, which are opposite to androgens.

One should know that both sexes produce androgens and estrogens. However, women produce much less androgens than men, whereas men produce much less estrogens than women.

Effects of androgens

  • Increase the excitability of psychosexual centers in central nervous system
  • Increase libido in both sexes
  • Strengthen erections in men and erection of clitoris in women
  • Lower blood glucose
  • Increase muscle mass and strength
  • Speed up regeneration of tissues
  • Increase the synthesis of proteins and inhibit their decay

Testosterone is a major male androgen. It forms a part of most anabolic compounds.
All organisms have different reaction to Androgens. It depends on receptor sensitivity to androgens. So the higher the sensitivity the smaller is the dose required for the same effect.

According to different reports, one can improve the sensitivity by:

  • Training with heavier weight
  • Consumption of high protein food
  • Taking L-caranitine (red meat, avocado, soy)

Side effects of Androgens

Androgens can induce the growth of already existing (undiagnosed) prostate cancer in men.They also may cause prostate enlargement, which doesn’t mean cancer, however it’s better to see a doctor in this case.

High doses of androgens may cause virilization (man-like features) in females– deepening of voice, excessive body hair growth, clitoris enlargement etc. Some of changes may disappear after discontinuation of the drug. However, some of them may stay (e.g. voice deepening and clitoris enlargement).

At high doses androgens can affect the sperm production in men. But this effect is transient and occurs only during the intake. Howbeit if you are planning to have children you should consult a doctor before taking these drugs.

Since Androgens are “male” hormones, the following side effects are quite natural:

  • deepening of voice
  • increased growth of hair on face and body
  • high sweat secretion
  • irritability, aggression

also in women:

  • decreased size of breast
  • irregular menstrual cycles
  • increase of female genitals

Less significant or temporary side effects:

  • Nausea
  • Dizziness
  • Headache
  • Weakness
  • Redness of the skin

Antiandrogens

Anti-androgen are substances that block androgen receptor, thus preventing the effect of androgens. They can slow down androgen-dependent types of cancer (e.g. prostate cancer) and shrink the tumors.

Nevertheless, they cannot stop androgen production. Anti-androgensare often used in combination with other treatments, such as surgical or chemical castration.

Side effects of anti-androgens:

  • Decreased libido
  • Depression
  • High levels of liver enzymes
  • Reduction of body hair
  • Birth defects if taken during pregnancy
  • Hepatitis
  • Liver injury
  • Erectile dysfunction
  • Diarrhea
  • Breasttenderness
  • Menstrual irregularity
  • Skin rash

Before taking these drugs ask your doctor to choose an anti-androgen with lowest side effects.

Conclusions

One should remember that anti-androgens cannot suppress all the androgenic side effects. Therefore, in case of androgenic side effects, it’s better to lower of using androgen containing drug.
Take anti-androgens only in extreme cases.

Do not forget about proper nutrition, healthy sleep and walking outdoors.

Estrogen related side effects

Steroid aromatization

Nowadays most athletes take steroids in order to get optimal results. However, the intake of AAS may lead to certain side-effects. Estrogen relatedside-effects caused by aromatization, are probably the most unpleasant ones.

Therefore, athletes are trying to find unaromatizable steroids, which is a misconception, as all steroids are aromatizable to some extent. Today we will regard the issues of aromatization and estrogen related side-effects.

Aromatization

One should understand that steroids do not cause aromatization. This is a naturally occuring process which converts testosterone into estrogens. The enzyme responsible for this conversion is called Aromatase. This is where the term “aromatization” comes from.

The major task of aromatization is the creation of cholesterol and fats. However, when the excessive amount of male hormone gets into the body, the organism tends to keep the balance, thus transforming it into estrogens.

In its turn, this transformation produces the excess of estrogens, which leads to gynecomastia, also known as gyno or “bitch tits”.Each organism has its own number of aromatase enzyme. The higher is this number, the more testosterone transforms into estrogens.

Therefore, athletes with high amount of aromatase enzyme has higher risks of estrogenic side effects. They should pay special attention to antiestrogens while going through steroid cycle.

Testosterone

Normally males produce around 7 mg of testosterone a day. However, it is not enough to cause massive muscle growth. But one can trigger this growth by taking exogenous testosterone. Since the usual dosage is around 100 mg, our body tries to get rid of the excess, by initiating aromatization.

Estrogen

It’s important to know, that both males and females produce estrogen. Though it is regarded as “female hormone”, it plays important role in males too. Estrogen is a natural steroid, which performs specific functions in male organism, including:

  • growth ofbones
  • development of reproductive system
  • regulation of body temperature
  • memory function
  • and even muscle growth in combination with testosterone.

Therefore, one shouldn’t regard it as “evil”. Estrogen is good when its amount is within norm, but when it is too high, it may lead to undesirable side effects.

Gynecomastia

It is estrogen that makes the shape of female body. As a sex hormone it helps females to mature for childbirth, breastfeeding, and pregnancy. Due to aromatization the intake of steroids without antiestrogens may elevate the level of estrogen in males.

This in turn causes growth of breast tissue and female type fat deposition. In other words, the excess of estrogens can reshape the male body into female one. Luckily one can easily avoid this unpleasant side effect by using antiestrogens.

Water retention

Excessive levels of estrogen may cause water retention, which means accumulation of water in the tissues of an organism. It makes your body look puffy. Thus, the lower is estrogenic property (aromatizability) of steroid you use, the less water your body keeps.

Thereby at the end of your steroid cycle, you will have more lean muscle mass and less rollback. Since antiestrogens can greatly reduce the rate of aromatization and prevent estrogenic side effects, they are very important for athletes taking steroids. Make sure that you have aromatase inhibitors and estrogen blockers in your cycle plan.

Other side effects

  • Vomiting
  • Muscle tightness
  • Dizziness
  • Weight changes
  • Weakness
  • Joint pain
  • reduction of immunity
  • cholesterol issues

Most Aromatizing Steroids

One should remember that all steroids are prone to aromatization. All of them aromatase but at different rate. Therefore, we are talking about most and less aromatizable steroids.

Also,such individual features as the number of aromatase enzyme in the organism may influence the rate of aromatization of certain steroids. This number can turn low aromatizable steroid into highly estrogenic.

Here is the list of steroids with high estrogenic activity.

Less Aromatizable Steroids

Antiestrogens

The following list of antiestrogensis recommended for use during the cycle or PCT in order to reduce estrogenic effect.

• Arimidex (Anastrozole) – aromatase inhibitor (during cycle)

• Femara (Letrozole) aromatase inhibitor (during cycle)

• Clomid (Clomiphene Citrate) blocker of estrogen receptor (PCT)

• :tamoxifene: blocker of estrogen receptor (PCT)

• HCG (Pregnyl (HCG – Human Chorionic Gonadotropin)) prevents the atrophy of testicle, during heavy cycles, which last more than 6 weeks

If youdecided to take steroids, you should be very attentive to the symptoms. Choose those substances, which are suitable for your body. Also it’s important to pay attention to your diet and sleep.

There are several reliable sources where you can buy anabolic steroids:

Sustanon 250 + Nandrolone Decanoate Stack Combination

Most bodybuilders prefer to use Testosterone esters in combination with Nandrolone Decanoate (Deca). Sustanon 250, as a mixture of testosterone esters, becomes a perfect candidate for this combination. In this article we will regard the properties of the Sustanon 250 + Nandrolone Decanoate combination and how to use it correctly.

First of all, it is significant to say that both drugs are very powerful substances which are widely used in bodybuilding for gaining of muscle mass. At the same time, this combination greatly increases strength. According to different reports during eight-week cycle (Sustanon + Deca) one can gain up to 10 kg and increase one’s strength by 25% of initial level.

Nandrolone Decanoate

Deca-Durabolin has low level of aromatization and very low androgenic properties. If it were not for the progestogenic activity, this steroid would definitely become one of the safest AAS.

This drug accelerates hypertrophy of muscle tissue, increases strength, improves joint-ligament system, increases absorbtion of nutrients in the digestive system, strengthens bones and makes immunity more efficient.

Sustanon 250

The steroid consists of four Testosterone esters, which have different half-life period. As a result, it has quick and prolonged effect at the same time. Its properties completely coincide with properties of Testosterone itself.

Anastrozole

As Testosterone esters are prone to aromatization, there is a risk of estrogen related side effects (e.g. gynecomastia). Therefore, in order to prevent them you should include anti-estrogens into your cycle. And Anastrozole is one of the most powerful drugs in this group.

It can greatly reduce the concentration of estrogens, as it inhibits the enzyme converting testosterone into estrogens (aromatase).

Gonadotropin

Since both steroid of this combination suppress the production of endogenous testosterone,it is necessary to take Pregnyl (HCG – Human Chorionic Gonadotropin). This drug maintains the function of testicles, thereby preventing their athrophy.

Cabergoline

This drug is necessary for the cycles including Nandrolone or Trenbolone. These steroids have progestogenic activity, which increases the concentration of female hormone prolactin. In males high levels of prolactin may lead to unpleasant consequences. Cabergoline induces the secretion of dopamine, which in its turn reduces the level of prolactin.

Clomid

You should do Post Cycle Therapy after each steroid cycle. For this combination we recommend Clomid, since Tamoxifenis not suitable for Nandrolonecycles. Clomidwill accelerate the recovery of testosterone producing system.

Dosage and Usage

The duration of this cycle is ten weeks. This time is enough to fully reveal the potential of Nandrolone, which has slow onset of its effects.

We advise you to stick to the following scheme:

  • From 1st to 10th week take 200mg of Nandrolone every seventh day
  • From 1st to 10th week take 500mg of Sustanon weekly
  • From 2nd to 12th week on the 8th day of your cycle start taking Anastrozole 0.5 mg every other day.
  • From 2nd to 12th week start taking 250mcg of Cabergoline every fourth day
  • From 8th to 12th week inject Gonadotropin 500 I.U. twice a week
  • 14th week start PCT with 100 mg of Clomid every day
  • From 15th to 16th week reduce the dosage of Clomid to 50 mg/day

The Nandrolone Decanoate and Sustanon 250 combination can produce a synergistic effect. If you follow these recommendations you can achieve excellent results without undesirable side-effects.

There are several reliable sources where you can buy anabolic steroids:

Dianabol and Nandrolone Decanoate stack for gaining muscle mass

athlet with pills
athlet with pills

Goals of combination

Dianabol and Deca-Durabolin is a classical combination for gaining mass and strength. If you follow the cycle properly, you can get up to 10 kg of muscle mass. Of course, this is the maximally possible result and it is not always achievable. However, in any case, this cycle will be effective and safe. Additionally this cycle may increase libido, improve endurance and strengthen joint-ligament system.

Characteristics of used drugs

Dianabol. The active ingredient of this steroid ismethandienone (methane). Athletes worldwide have been using this substance for more than six decades. Dianabol is good for gaining muscle mass and increasing strength.

Opponents of this steroid often indicate on itshigh hepatotoxicity. However, it was scientifically proved that at reasonable doses (30 – 40 mg daily) it is not toxic to the liver.

Nandrolone Decanoate (Deca-Durabolin). Along with methane, it is one of the most popular AAS among bodybuilders. Though itsanabolic action unfolds slowly enough, the final results can amaze an athlete. It also strengthensjoint-ligament system, and besides, improves immune system.

Proviron (Masterlone). Theactive substance of this drug is Masterolone, which belongs to a group ofantiestrogens. Proviron can effectively inhibit the enzyme aromataze, which converts testosterone into estrogens.
Due to the action of this enzyme, the levels of estrogen increase and estrogen-related side-effects become possible (e.g. gynecomastia).

Though this drug is not as powerful as other representativesof this group, its usage in this cycle is completely justified. The thing is that Decais almost unaromatizable, meanwhile methane has low rate of conversion.

Therefore, there is no need for more powerful antiestrogens (e.g. Exemestane). Their usage is necessary only in case of athlete’s genetic predisposition to aromatization.

Clomid. You shouldn’t use tamoxifenafter Nandrolone Decanoate cycle. Thus, you can choose only between toremifene and Clomid. Though their anti-estrogenic activity almost do not differ, the latter is more available.

Rules of providing course Dianabol and Nandrolone Decanoate

In order to make your cycle effective and safe, one should choose right dosage. We suggest you to use both steroids at moderate doses, which guarantees no side-effects. The length of a cycle is 5 weeks. This is enough for beginners. Experienced athletes can extend it up to 8-10 weeks.

Take Dianabol gradually increasing the dosage from 20 to 40mg/day, then gradually decrease the dosage in the same way. This “up-and-down-the-hill” pattern will help your body to adapt to this steroid.
In order to improve effectiveness of Dianabolit’s better todissolve the tablets under the tongue, rather than swallowthem. To make smooth hormonal background divide the daily dosage into several portions and take them at regular intervals.

The weekly dosage of Nandrolone Decanoate (Deca-Durabolin) is 0.4 grams. Therefore, the usual pattern of Deca-Durabolin administration is 200mg every third day. For example, you can take it on Mondays and Thursdays. This pattern will ensure a steady flow of steroid into the blood.

Take Proviron (Masterlone) starting from the second or third week of your cycle and go on until steroid withdrawal. The daily dose is 50 mg. Start PCT in seven days since last Decainjection. The daily dosage of Clomid is 50 milligrams. In most cases, three weeksis sufficient time for your body to restore.

You can find a lot of positive reviews about stacking of Dianabol and Deca-Durabolin the internet. It is not surprising, since the cycle provides excellent results and safetyat the same time.

If you follow the recommended dosagesand take auxiliary drugs, there will not be side-effects. The rollback after the cycle is minimal, which is important. Some novice bodybuilders complain about the loss of gained mass after steroid withdrawal.

This happens due to the wrong cycle. We have to remind that by using Proviron you not only suppress estrogen-related side-effects, but also water retention. As a result, your muscles do not swell. Therefore, after steroid withdrawal there are no losses.

If your cycle is long enough, take Dostinex in order to avoid progestogenicside-effects of Deca. This cycle is suitable not only for beginners, but also for experienced bodybuilders.

There are several reliable sources where you can buy anabolic steroids: